Toxins and Diluents

Order botulinum toxin medicines and clinical diluents from Longeva Pharma for eligible UK healthcare and aesthetic professionals.

Our professional range includes BOTOX®, Azzalure®, Alluzience®, BOCOUTURE®, Letybo®, Relfydess® and Nuceiva®, alongside sodium chloride and other associated diluents. Access and supply are subject to the professional, account and prescription requirements applicable to each product.

Botulinum toxin brands for UK aesthetic professionals

Browse Azzalure, Letybo, BOCOUTURE, BOTOX, Alluzience and Relfydess and Nuceiva. Each medicine has its own authorised product information, potency units, presentation and storage requirements and should be prescribed, prepared and administered in accordance with the current Summary of Product Characteristics.

Direct professional product routes: BOTOX 50 · BOTOX 100 · Azzalure Single · Azzalure Dual · Alluzience Single · Alluzience Two Vials · BOCOUTURE 50/100 · Relfydess · Letybo · Nuceiva.

Shop toxin ranges by manufacturer

Move between the category and the relevant manufacturer hubs: Galderma for Azzalure, Alluzience and Relfydess; Allergan Aesthetics for BOTOX; Merz Aesthetics for BOCOUTURE; and Croma for Letybo.

Toxins requiring reconstitution and ready-to-use toxins

Some botulinum toxin medicines are supplied as a powder for solution for injection and require reconstitution in accordance with their current product information. Others, including certain ready-to-use presentations, do not require reconstitution. This collection therefore includes both botulinum toxin medicines and associated clinical diluents such as sodium chloride. Product-specific preparation requirements should always be checked before prescribing or administration.

Ordering prescription botulinum toxin through Longeva Pharma

Prescription-only medicines are supplied only through the appropriate pharmacy process and against a valid prescription where required. Professional access, prescription requirements and pharmacist review apply before medicines can be dispensed or supplied. Practitioners can register for professional access, review our prescribing information and browse the wider Prescription-only medicines collection.

Faces and Greater Manchester local supply

Practitioners using Faces can browse selected products through our Faces collection. Greater Manchester clinics with an urgent local requirement can review same-day delivery and pre-arranged collection, subject to stock, confirmation and applicable pharmacy requirements.

Practitioner guides

For further guidance, read who can prescribe botulinum toxin in the UK, Patient Specific Directions (PSDs) in aesthetics, common aesthetic prescription errors and our current toxin storage comparison.

Healthcare professionals should consult the current Summary of Product Characteristics before prescribing, preparing or administering any medicine. Suspected adverse reactions can be reported through the MHRA Yellow Card scheme.

Local pharmacy supply and practitioner resources

Eligible Greater Manchester clinics can enquire about same-day delivery and pre-arranged Rochdale collection. See our Faces professional collection, botulinum toxin brand comparison, cold-chain storage guide and GPhC registration guide. Prescription-only medicines remain subject to the appropriate lawful prescription and pharmacy checks.

Considering a change of professional pharmacy? Visit our Switch to Longeva Pharma guide and independent supplier comparisons.

Azzalure, Alluzience and Relfydess: compare professional toxin presentations

Choosing a suitable botulinum toxin involves understanding each medicine's licensed use, presentation, preparation and product-specific potency units. Our Azzalure vs Alluzience practitioner comparison explains key differences, including reconstitution and ready-to-use formulations. For clinics in Greater Manchester, see our same-day toxin and diluent supply guide and local delivery and collection service. Supply of prescription-only medicines is restricted to eligible professionals through appropriate prescription and pharmacy processes.

Order directly, through Faces, or arrange Greater Manchester collection

Eligible practitioners can access our professional toxin range directly through Longeva Pharma or discover selected products via Longeva Pharma on Faces. If your clinic is in Greater Manchester, ask about same-day delivery or pre-arranged local collection; see the local toxin supply guide for how it works. Availability and fulfilment must be confirmed with the pharmacy and all prescription and professional requirements apply.

UK botulinum toxin brands, prices and professional ordering

Compare the existing Azzalure, BOTOX, BOCOUTURE, Alluzience, Relfydess, Letybo and Nuceiva listings for eligible UK practitioners. Searches such as Azzalure Botox, BOCOUTURE Botox, Relfydess Botox and Letybo Botox refer to distinct botulinum toxin medicines, not necessarily BOTOX brand. Potency units are product-specific and not interchangeable.

For buy Azzalure, Azzalure 125 units price and Galderma Azzalure, choose the single 125-unit vial or dual pack. For BOTOX 50 units or BOTOX 100 units price UK, visit our BOTOX collection. For BOCOUTURE 50 or 100 units, visit BOCOUTURE. Explore Letybo 50 units and the remaining toxin products displayed above.

Botulinum toxin diluents and reconstitution supplies

For TOR-BAC saline, bacteriostatic sodium chloride and sodium chloride 0.9% 10ml, browse the existing Diluents collection. Different diluents are not automatically interchangeable: consult the individual toxin SmPC before preparation. Professional eligibility, prescription and pharmacist review apply where required. Greater Manchester same-day delivery and collection are subject to confirmation.

Professional pharmacy ordering — Toxins and Diluents

Browse existing product presentations and check current availability and pricing before ordering. Prescription-only botulinum toxin medicines are supplied subject to professional eligibility, an appropriate prescription and pharmacist review.

Shop the relevant products: Azzalure 125 single · Azzalure 125 dual · BOTOX 100 · BOTOX 50 · BOCOUTURE · Alluzience single · Alluzience dual · Relfydess · Letybo 50 · Nuceiva 50.

See Toxins and Diluents, Diluents and Greater Manchester same-day delivery and collection (subject to eligibility and confirmation).

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Frequently asked questions

What is Botulinum Toxin?
Botulinum toxin is prescription-only medicines containing botulinum toxin type A. They temporarily reduce muscle activity by inhibiting the release of acetylcholine at the neuromuscular junction.

Different brands have different formulations, licensed indications and potency units. Botulinum toxin units are product-specific and should not be directly converted between different brands.
What Botulinum Toxin brands are available from Longeva?
Our range may include leading UK-licensed botulinum toxin products such as Azzalure, BOTOX, Bocouture, Letybo and other products subject to availability.

Availability can change, so please view our current Toxins & Diluents collection for the latest range.
What is the difference between Azzalure, Botox, Bocouture and Letybo?
Azzalure, Botox, Bocouture and Letybo are different branded botulinum toxin type A medicines.

Although they have the same broad mechanism of action, they differ in formulation, potency units, vial presentations, licensed indications and prescribing information.

Importantly, their units are not interchangeable. Practitioners should always follow the dosing information for the specific product being prescribed.
Are Botulinum Toxin units interchangeable?
No.

Botulinum toxin potency units are specific to each manufacturer’s product and are not directly interchangeable.

For example, Azzalure uses Speywood units, while Botox uses Allergan Units. Bocouture has its own product-specific units.

Always refer to the relevant SmPC when calculating or administering a dose.
What is reconstitution?
Reconstitution is the process of adding the specified diluent to a powdered botulinum toxin vial to prepare the solution for injection.

The appropriate diluent and volume depend on the individual product and vial size. Always follow the current manufacturer’s SmPC.
What diluent is used to reconstitute Botulinum Toxin?
The diluent specified for many powdered botulinum toxin products is sterile 0.9% sodium chloride solution for injection.

However, the required volume can vary between products and vial sizes.

Always check the current product information before reconstitution.
Can I use the same dilution for every Botulinum Toxin?
No.

Different botulinum toxin products and vial sizes may have different recommended reconstitution volumes and resulting concentrations.

The reconstitution instructions for Azzalure, Botox, Bocouture and Letybo should therefore not be assumed to be interchangeable.
How much saline is used to reconstitute Azzalure?
For Azzalure 125 Speywood units, the product information provides specific reconstitution options using 0.9% sodium chloride solution.

For example, the manufacturer’s information describes:

* 0.63 mL of sodium chloride 0.9% to produce 10 Speywood units per 0.05 mL
* 1.25 mL of sodium chloride 0.9% to produce 10 Speywood units per 0.1 mL

Always refer to the latest Azzalure SmPC before preparation or administration.
Does changing the amount of saline change the number of units in the vial?
No.

Changing the volume of diluent changes the concentration of the resulting solution, but does not change the total number of botulinum toxin units contained within the vial.

The resulting concentration should always be calculated and checked carefully before administration.
How should Botulinum Toxin be stored?
Storage requirements vary according to the individual product.

Many botulinum toxin products require refrigerated storage at 2–8°C, while some products have different permitted storage conditions.

Always check the specific product’s SmPC and packaging requirements.
What does fridge-line mean?
Fridge-line refers to products that require controlled refrigerated storage and transportation.

Where a product is classified as fridge-line, appropriate temperature control must be maintained throughout storage and delivery in accordance with the manufacturer’s requirements.
Why is my order delivered in temperature-controlled packaging?
Temperature-controlled packaging helps maintain the required storage conditions during transportation.

This is particularly important for fridge-line medicines, including certain botulinum toxin products.
What should I do if my Botulinum Toxin arrives warm?
Do not automatically assume that the product is unusable.

Temperature excursions should be assessed against the specific product’s stability and storage information.

If you are concerned about the temperature of your delivery, contact Longeva Pharmacy before using the product and retain the packaging and product information for assessment.
How long can reconstituted Botulinum Toxin be stored?
This varies according to the individual product.

The manufacturer’s SmPC should always be consulted for the approved storage period and conditions following reconstitution.

Microbiological considerations should also be taken into account, and practitioners should follow appropriate infection-control and aseptic procedures.
Who can purchase Botulinum Toxin from Longeva?
Botulinum toxins are prescription-only medicines.

Longeva supplies prescription-only medicines in accordance with applicable UK medicines legislation and professional requirements.

Practitioner accounts are subject to appropriate verification, and access to prescription-only products may require relevant professional information.
Why do I need to register for a practitioner account?
Longeva operates a professional healthcare supply service.

Registration allows us to verify relevant practitioner and professional details before providing access to prescription-only medicines and professional pricing.