UK aesthetic practitioners now work with several botulinum toxin type A medicines. BOTOX®, Azzalure®, BOCOUTURE®, Letybo®, Alluzience® and Relfydess® are distinct medicines with their own product information, potency units, presentations, preparation requirements and authorised indications.
This guide provides a practical starting point for comparing the brands. It is not a substitute for the current Summary of Product Characteristics or individual clinical judgement.
BOTOX
BOTOX is supplied in presentations including 50 and 100 Allergan Units. Its units are product-specific. Practitioners should follow the current product information for storage, reconstitution and administration.
Azzalure
Azzalure is supplied in 125 Speywood Unit vials. Speywood Units are specific to the product and should not be converted or treated as interchangeable with the units used by another botulinum toxin medicine.
BOCOUTURE
BOCOUTURE is available in presentations including 50 and 100 units. It is supplied as a powder for solution for injection and should be prepared in accordance with its current product information.
Letybo
Letybo is available as a 50-unit presentation. As with every botulinum toxin medicine, practitioners should use the product-specific potency, reconstitution, storage and administration information.
Alluzience
Alluzience is a ready-to-use solution for injection, distinguishing its presentation from toxins supplied as powders requiring reconstitution. Its potency units and administration information remain product-specific.
Relfydess
Relfydess is also supplied as a ready-to-use solution for injection. Practitioners should consult its current authorised product information for indications, potency, storage and administration.
Ready-to-use vs reconstituted botulinum toxins
Presentation is one of the clearest practical differences between the available medicines. Some products require reconstitution before administration, while ready-to-use products remove that preparation step. That does not make the medicines interchangeable: prescribing and administration must remain product-specific.
Which botulinum toxin should a practitioner choose?
There is no single answer appropriate to every patient or practitioner. Selection is a clinical prescribing decision that should consider the individual patient, authorised indications, current product information, practitioner familiarity and other relevant clinical factors.
Ordering through a UK pharmacy
Botulinum toxin medicines are prescription-only medicines. Longeva Pharma supplies eligible UK healthcare and aesthetic professionals through a professional pharmacy process, subject to pharmacist review and a valid prescription where required.
Browse BOTOX, Azzalure, BOCOUTURE, Letybo, Alluzience and Relfydess, or read our guide explaining who can prescribe botulinum toxin in the UK.
Key point
Brand familiarity should never lead to assumptions about equivalence. Check the current SmPC for the specific medicine before prescribing, preparing or administering it.